GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THCA | trans | rs1056667 | 1 | rs6932156 | chr6:26571506 | ZNF322B | chr9:99957633-99961910:- | 0.59 | 11.32 | 1.79E-26 | Educational attainment |
| THCA | trans | rs1056667 | 1 | rs6933176 | chr6:26540178 | ZNF322B | chr9:99957633-99961910:- | 0.54 | 10.32 | 1.12E-22 | Educational attainment |
| THCA | trans | rs1056667 | 1 | rs6940053 | chr6:26562122 | ZNF322B | chr9:99957633-99961910:- | 0.58 | 11.36 | 1.17E-26 | Educational attainment |
| THCA | trans | rs1056667 | 1 | rs6940188 | chr6:26562029 | ZNF322B | chr9:99957633-99961910:- | 0.58 | 11.36 | 1.27E-26 | Educational attainment |
| THCA | trans | rs965513 | 1 | rs7020976 | chr9:100547972 | BMPR1A | chr10:88516396-88684944:+ | -0.24 | -6.18 | 1.35E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7020976 | chr9:100547972 | CLDN2 | chrX:106143394-106174091:+ | 0.26 | 6.06 | 2.81E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7020976 | chr9:100547972 | EML5 | chr14:89081205-89259157:- | 0.3 | 6.86 | 2.11E-11 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7020976 | chr9:100547972 | EPDR1 | chr7:37960163-37991539:+ | 0.32 | 7.11 | 4.19E-12 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7020976 | chr9:100547972 | GGT5 | chr22:24615623-24641110:- | 0.26 | 5.94 | 5.54E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7020976 | chr9:100547972 | LRRC42 | chr1:54412037-54433839:+ | -0.23 | -6.05 | 2.94E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7020976 | chr9:100547972 | NKX6-1 | chr4:85414436-85419387:- | 0.5 | 8.83 | 2.07E-17 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7020976 | chr9:100547972 | PLCE1 | chr10:95753746-96088146:+ | 0.27 | 6.13 | 1.81E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7021576 | chr9:100540541 | CD302 | chr2:160625141-160654766:- | 0.24 | 5.98 | 4.43E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7021576 | chr9:100540541 | CLDN2 | chrX:106143394-106174091:+ | 0.27 | 6.11 | 2.11E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7021576 | chr9:100540541 | EML5 | chr14:89081205-89259157:- | 0.3 | 6.77 | 3.71E-11 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |